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Urinary Incontinence

Urinary incontinence is classified as the involuntary loss of urine. It has been estimated that it affects as many as 13 million Americans and that 10 to 30% of all US women aged 15 to 64 and 50% of all female nursing home patients are affected with the condition. 

Around the globe, urinary incontinence is widespread. In Asian nations, between 4% (China) and 17% (Singapore) of all women are affected. Between 15 and 34% of all European women experience some form of urinary incontinence. The overall average worldwide rate of urinary incontinence for men and women is greater than 25% and is approximately 15% for all women world wide. The prevalence of urinary incontinence tends to be higher in women than in men due to anatomical differences as well as the fact that women experience pelvic trauma during childbirth. The number of women with urinary incontinence of any type increases with age. Younger age group cohorts tend to reflect a lower percentage while post menopausal women tend to yield a higher percentage.

In order to understand urinary incontinence, one must understand the anatomy and physiology of the urogenital system. Normal bladder control is maintained by the bladder and urinary sphincter as they work together as a valve. The urethra and urinary sphincter muscle relax and open, the bladder opens, and urine passes. The bladder neck and urethra are under muscular control with the lower portion of the sphincter tightening to maintain continence. When surrounding tissue is compromised or weakened, there is lack of bladder neck support and incontinence is the result.

The primary causes of urinary incontinence are:

  1. Bladder related: caused by the bladder's failure to store, failure to empty, or both; reduced capacity, involuntary contractions, poor bladder compliance. 
  2. Sphincter related: poor positioning of the bladder neck in women, uncoordinated bladder sphincter action, sphincter damage or weakness, outlet obstruction. 

There are three major types of incontinence which are based on the characteristics of the disorder:

  1. Stress: caused by weak external sphincter and pelvic floor muscles and an unsupported bladder neck. 
  2. Urge: causes may be neurological in origin; bladder is overly sensitive and may contract unexpectedly. 
  3. Overflow: continual leakage from an overly full bladder that never empties completely. 

Pharmacologic therapy is generally used in the treatment of urge incontinence due to the fact that the underlying causes of urge incontinence are primarily related to neuromuscular dysfunction. These drugs, while effective, produce a variety of untoward side effects of varying degrees. Stress incontinence is typically treated surgically, however anticholinergics found in common decongestants seem to be effective in patients with poor muscle tone and poorly functioning sphincters. 

FemmePharma Global Heathcare, Inc. is dedicated to helping the millions of women suffering from urinary incontinence.

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